Searchable abstracts of presentations at key conferences in endocrinology

ea0026p194 | Pituitary | ECE2011

Immunopositive ACTH cells in juvenile female rats after treatment with estradiol

Milosevic V , Ajdzanovic V , Todorovic D , Sosic-Jurjevic B , Filipovic B , Nestorovic N , Pantelic J , Sekulic M

It was shown that estrogens decreased the POMC gene expression level in female rats. The aim of the present study was to examine the morphometric parameters of immunohistochemically labeled ACTH cells in juvenile female rat pituitaries after estradiol dipropionate (EDP) treatment. The females in juvenile period (16th day) were divided into two groups, each of seven animals. The experimental group received five injections of EDP (i.p. 0.25 mg/kg b.w.) every second day from the ...

ea0026p1 | Adrenal cortex | ECE2011

Pituitary–adrenal axis in male rats after exposure to high ambient temperature

Percinic-Popovska F , Ajdzanovic V , Trifunovic S , Jordanova M , Ilieski V , Pendovski L , Milosevic V

The global warming and its impact on the summer average temperature elevation, in the south-eastern parts of Europe, represent an inevitable stress for living organisms in this region. Heat stress was shown to be the strongest one, when compared to immobilization or cold stress. Activation of the hypothalamo-pituitary–adrenal (HPA) axis during exposure to various types of stressors is well-known physiological concept. The effect of 24 h exposure to heat stress on the morp...